Каприл инструкция применения таблетки взрослым

Kapril Tablet is a prescription medicine that is used to treat high blood pressure, signs of heart failure (symptomatic heart failure), kidney damage due to the presence of high amounts of proteins in urine in diabetic patients, kidney damage due to increased levels of urine albumin in diabetic patients. This medicine is also used to treat kidney failure and presence of protein in the urine in patients without diabetes mellitus. It works by blocking the hormone system that controls the blood pressure and fluid balance (called as, renin-angiotensin-aldosterone system). It helps by lowering the blood pressure. Kapril Tablet is also used to reduce the risk of heart attack, stroke and other fatal conditions associated with heart diseases.

Kapril Tablet may also be used along with other medicines in the treatment of certain conditions as recommended by the doctor. It is used with thiazide diuretics to treat high blood pressure. It is also used together with other antihypertensive, antiplatelet drugs, or Lipid lowering drugs to reduce the risk of heart attack, stroke and other fatal conditions associated with heart diseases.

Read the medicine guide provided by your pharmacist, your doctor, or the medicine company. If you have any questions related to Kapril, ask your doctor or pharmacist. Use Kapril Tablet as per the instructions provided by your doctor.

You should keep track of your blood pressure levels regularly. Share results with the doctor and discuss your treatment plan if your measurements areabnormally high or low

Kapril is eaten with or without food. Kapril capsules should be swallowed whole. It can also be taken by mixing with a small amount (4 ounces approx) of applesauce or mixed in 120 ml (4 ounces) of water or apple juice. These mixtures can be stored at room temperature for 24 hours or under refrigeration for 48 hours.

The typical dose of Kapril for adults is 2.5 mg to 20 mg once daily and dose may be adjusted after 2 to 4 weeks based on patient’s blood pressure response. The maximum dose for adult patients of Kapril is 10 mg once daily per day. Kapril is commonly used at the same time every day.

This medicine is to be used for longer periods of time.

Discuss with your doctor if your condition worsens. Discuss with your doctor if burning sensation, hair loss, dark concentrated urine, swollen mouth, difficulty while focusing, low blood sodium level, breast enlargement in men, slowed reactions, muscle cramps, fits, confusion, low blood cell count, and altered smelling sensations. If you have any kidney disease, In patients with abnormal functioning of the kidney, the recommended initial dose of Kapril is 1.25 mg once daily. Dosage may be increased up to the maximum dose of 5 mg by controlling high blood pressure conditions. If you have issues with the health of your liver, In patients with the abnormal functioning of the liver, the maximum daily dose of 2.5 mg Kapril is given under close supervision.

Your doctor may prescribe a lower starting dose of this medicine to understand the impact on the body. Please follow your doctor’s recommendations. Older patients may see an increase in the incidence of side-effects. As a result, a lower dose may be recommended for older patients.

The safety and effectiveness of using Kapril Tablet in children has not been established. No safety and effectiveness data has been established in children.

Consult with your doctor on the consumption of alcohol with Kapril.

Medicines may be recommended for uses other than those listed in the medicine guide. You should not use Kapril Tablet for conditions or symptoms for which it was not prescribed. Do not give Kapril Tablet to other people, even if they have the same conditions or symptoms that you have. The use of this medicine without the advice of a doctor may cause harm.

Follow storage instructions on the product package if available. Store Kapril Tablet at 15° to 30°C (59° to 86°F) for #NAME capsules, 20° to 25°C (68° to 77°F) for Kapril tablets, and away from moisture. Store this medicine away from children and pets.

Kapril Dosage

Dosage for high blood pressure

Adult

• Recommended: 2.5 mg to 20 mg once daily in one or two equally divided doses based on the patient’s response
• Initial: 2.5 mg once daily

Older Adults

• Initial: 1.25 mg

Dosage for signs of heart failure

Adult (patients taking diuretics)

• Recommended: an initial dose of Kapril should be double every one to two weeks up to 10 mg daily
• Initial: 1.25 mg daily
• Maximum: 10 mg daily

Older Adults

• Initial: 1.25 mg

Dosage for reduce the risk of heart attack, stroke and other fatal conditions associated with heart diseases

Adult

• Recommended: 5 mg once daily for three weeks after the initial dose and based on the patient’s response increased up to 10 mg once daily or it may be given in divided doses in patients with recently had a heart attack or high blood pressure
• Initial: 2.5 mg once daily for 1 week

Older Adults

• Initial: 1.25 mg

Dosage for kidney damage due to increased levels of urine albumin in diabetic patients

Adult

• Recommended: 2.5 mg once daily based on patient’s response after two weeks of initial dose and 5 mg once daily after further two weeks
• Initial: 1.25 mg once daily

Older Adults

• Initial: 1.25 mg

Dosage for kidney failure and presence of protein in the urine in patients without diabetes mellitus

Adult

• Recommended: 2.5 mg once daily based on patient’s response after two weeks of initial dose and 5 mg once daily after further two weeks
• Initial: 1.25 mg once daily

Older Adults

• Initial: 1.25 mg

Dosage for kidney damage in diabetic patients with risk factor of heart disease

Adult

• Recommended: 5 mg once daily based on patient’s response after one or two weeks of initial dose and 10 mg once daily after further two or three weeks
• Initial: 2.5 mg once daily

Older Adults

• Initial: 1.25 mg

Forms

Special Instructions

Missed Dose

Skip the missed dose if it’s time for next dose. Avoid taking a double dose to make up for the missed dose.

Overdose

If you think you have overdosed on Kapril Tablet, call a poison control center immediately. You can look up the poison control center information from the Poison Center Finder at TabletWise.com.

Before you use Kapril Tablet, tell your doctor if you are allergic to it or its ingredients. Your doctor may prescribe an alternative medicine and update your medical records to record this information. Tell your doctor if you are allergic to angiotensin converting enzyme inhibitor.

Before you use Kapril, tell your doctor of your medical history including swelling due to fluid accumulation, previous history of in utero exposure to Kapril, women in their last 6 months of pregnancy, abnormal functioning of the kidneys, patients with low or unstable blood pressure conditions, patients undergone dialysis procedures, or diabetes. Use of Kapril in patients with a history of swelling of the lower layer of skin may lead to further complications. Infants with a history of in utero exposure to Kapril may lead to low blood pressure, decreased urine production, and increased potassium levels in the blood (hyperkalemia). Before having any surgery when using Kapril, tell your doctor and dentist about all the medicinal products you use including prescription and non-prescription medicines, and any herbal supplements.

The use of this medicine may change potassium levels. An increase in the potassium level occurs while using Kapril. Caution should be used while using Kapril with potassium supplements and potassium-sparing diuretics. Also, the blood potassium level should be monitored regularly.

The use of Kapril Tablet may change creatinine level in the blood. An increase in the creatinine level occurs while using Kapril with a diuretic.

The use of this medicine may change blood urea nitrogen. An increase in the blood urea nitrogen level occurs while using Kapril with a diuretic.

The use of this medicine may change aldosterone. A decrease in the aldosterone level occurs while using Kapril.

The use of Kapril Tablet may change hemoglobin and hematocrit value. A decrease in hemoglobin and hematocrit level has been seen in patient’s while using Kapril and a diuretic.

Consult with your doctor on the consumption of alcohol with Kapril Tablet. Drinking alcohol may cause low blood pressure, dizziness, and light-headedness.

Kapril Tablet is not safe for use in pregnant women. If you are pregnant or planning to become pregnant, you should discuss with your doctor the impact this medicine may have on the baby before you start to use this medicine. Kapril can cross the placenta. The use of Kapril in the second and third trimester of pregnancy causes a decrease in the functioning of kidneys and increases chances of fatality in the unborn baby. It can also result in a deficiency of amniotic fluid in womb associated with incomplete development of lungs and bone deformations. Other side effects caused by Kapril include skull abnormalities, less production of urine, low blood pressure, kidney failure, and other defects in the baby. Kapril Tablet is not safe for use in women who are breastfeeding. If you are breastfeeding, discuss with your doctor if you should either discontinue breastfeeding or stop using this medicine while breastfeeding. Kapril and its metabolites may pass into breast milk if given in multiple doses. The information available on the use of Kapril in women who are breastfeeding is not sufficient. Consult with your doctor on the use of Kapril Tablet, if you are trying to conceive.

Kapril Tablet can make you feel sleepy. Be careful while driving, using machinery, or doing any other activity that needs you to be alert. The consumption of alcohol with Kapril Tablet can make you feel more sleepy. Kapril Tablet may cause seizures in some people. Discuss with your doctor if you perform activities where a loss of consciousness may cause you or others harm.

This medicine may increase your sensitivity to sunlight. If this happens, limit your time outdoors and do not tan to prevent sunburns. Cover your skin when you are outdoors or use a sunscreen. In case you get a sunburn, consult with your doctor.

Kapril Tablet may cause an increased risk of side-effects in younger patients. Children using this medicine may see an increased risk of fast heartbeat, nasal congestion, stuffy nose (rhinitis), pink eye (conjunctivitis), tremor, and hives.

Your doctor has prescribed this medicine because they judge that the benefit is greater than the risk posed by side-effects. Many people using this medicine do not have serious cases of side-effects. This page does not contain a complete list of all possible side-effects.

If you experience side-effects or notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority. You can look up the drug authority contact information from the Drug Authority Finder at TabletWise.com.

Use of telmisartan with Kapril

Patients using telmisartan and Kapril in combination are at increased risk. These patients have higher chances of developing abnormal functioning of the kidneys. The combined use of telmisartan and Kapril is not recommended.

Non productive, persistent cough

Patients using ACE inhibitors are at increased risk of non productive and persistent episodes of cough.

High blood potassium level (hyperkalemia)

Patients with high blood pressure are at increased risk when using this medicine. Also, the patients with diabetes mellitus, kidney insufficiency, and the combined use of potassium-sparing diuretics, potassium-containing salt substitutes, and potassium supplements are at increased risk. These patients may suffer from high potassium levels in the blood. Take necessary precautions while using this medicine in such patients.

Women in their second and third trimester of pregnancy

Women who are pregnant are at increased risk when using this medicine. Kapril can cross the placenta. The use of Kapril in the second and third trimesters of pregnancy causes a decrease in the functioning of kidneys and increases the chances of fatality in the unborn baby. It can also result in a deficiency of amniotic fluid in womb associated with incomplete development of lungs and bone deformations. Other side effects caused by Kapril include skull abnormalities, less production of urine, low blood pressure, kidney failure, and other defects in the baby. When pregnancy is detected, stop using Kapril. Appropriate management of high blood pressure in the mother during pregnancy should be done. If no alternative therapy is available, tell the mother about the risk of deficiency of amniotic fluid and perform ultrasound regularly. Closely observe babies with a history of in utero exposure to Kapril for symptoms of low blood pressure, less urine production, and increased potassium levels.

Decreased white blood cells count

Patients with inflammation of connective tissues (collagen vascular disease) and kidney dysfunction are at increased risk when using this medicine. These patients may develop a reduction in the white blood cell count, red blood cell count, and hemoglobin content, or platelet count. In this case, proper monitoring of white blood cells should be considered in patients with collagen vascular disease, mainly if the condition involves abnormal functioning of kidney.

Liver failure

Patients using ACE inhibitors are at increased risk. These patients may develop jaundice due to reduced bile flow (cholestatic jaundice) and progresses to acute liver failure (fulminant liver necrosis) and fatality. Discontinue the use of Kapril in patients with jaundice or increased liver enzymes. An appropriate medical check-up is required in such patients.

Low blood pressure

Patients with salt depleted as a result of prolonged diuretic therapy, dialysis, dietary salt restriction, diarrhea, or vomiting are at increased risk when using this medicine. Patients with congestive heart failure with or without kidney insufficiency are also at the increased risk when using this medicine. These patients may develop signs of low blood pressure which may be associated with reduced urination or abnormally raised level of nitrogen-containing compounds (azotemia) and very rarely it may lead to acute kidney failure and fatal conditions. If this happens, the patient should be placed in a lying position. If required, treatment with intravenous physiological saline infusion should be given. The close supervision is necessary for the first two weeks of the treatment.

Swelling of intestine due to fluid accumulation

Patients using angiotensin-converting enzyme inhibitors are at increased risk. These patients may suffer from abdominal pain with or without vomiting or nausea.

Swelling of the face, head, mouth and neck extremities

Patients with a history of swelling of the lower layer of the skin are at increased risk when using this medicine. These patients may suffer from swelling due to fluid accumulation on the face, lips, extremities, glottis, tongue, and larynx. If this happens, discontinue using this medicine and appropriate treatment should be given immediately. In case, if there is an involvement of the glottis, tongue, or larynx it may lead to airway obstruction and to prevent this subcutaneous epinephrine solution 1:1,000 (0.3 ml to 0.5 ml) can be used.

Severe allergic reactions (anaphylactoid reactions)

Patients undergoing desensitizing treatment (to reduce or eliminate an organism’s negative reaction to a substance) with insect venom (Hymenoptera venom) and purification procedure with high-flux membranes are at increased risk when using this medicine. Also, the patients undergoing low-density lipoprotein apheresis using dextran sulfate are at increased risk. These patients may suffer from serious side-effects. If this happens, temporarily discontinue using this medicine.

Use of aliskiren with Kapril

Patients with diabetes or abnormal functioning of the kidneys are at increased risk when using this medicine. These patients may suffer from low blood pressure, high potassium, and changes in the functioning of the kidney. Kapril should not be used in combination with aliskiren.

Surgery

Patients using Kapril during surgical procedures are at increased risk. It is advised that the treatment with Kapril should be stopped one day before the surgery, if possible.

Soya warning

Patients who are allergic to peanut or soya are at increased risk when using this medicine. These patients should not use this medicine.

Patients with kidney disease

Patients having high blood pressure with narrow kidney arteries and the patients using diuretics are at increased risk when using this medicine. These patients may suffer from increased levels of blood urea nitrogen and creatinine. If this happens, reduction in the dose of Kapril and discontinuation of diuretics is required.

When two or more medicines are taken together, it can change how the medicines work and increase the risk of side-effects. In medical terms, this is called as a Drug Interaction.

Your doctor’s guidelines may need to be followed while taking this medicine along with angiotensin II receptor blocker or aliskiren, which are used to treat high blood pressure. The use of Kapril with angiotensin II receptor blocker or aliskiren may cause side-effects such as low blood pressure, increased potassium level and decreased functioning of the kidneys. Avoid the combined use of Kapril with angiotensin II receptor blocker or aliskiren in patients with diabetes or abnormal functioning of the kidneys.

Kapril Tablet interacts with non-steroidal anti-inflammatory agents, which are used to reduce fever, treat pain and blood clots. When Kapril is used with non-steroidal anti-inflammatory agents including selective cyclooxygenase-2 inhibitors in elderly, kidney disease or volume-depleted patients, it may reduce the blood lowering effect of Kapril or cause kidney failure. The functioning of the kidney should be regularly monitored in such patients.

There may be an interaction of Kapril with gold, which is used to treat pain associated with swelling and stiffness of the joints. The use of Kapril with gold injection (sodium aurothiomalate) may cause symptoms such as nausea, vomiting, facial flushing, and low blood pressure.

Special instructions need to be followed while taking this medicine along with lithium, which is used to treat mental disorders. Kapril may reduce the excretion of lithium and thus may enhance the lithium level in the blood. In case if the diuretic is used along with these medicines, further adds more risk to increased level of lithium in the blood. Take precaution and monitor lithium level while using Kapril together with lithium.

Your doctor’s guidelines may need to be followed while taking this medicine along with antidiabetic agents including insulin, which are used to treat high blood sugar levels. When antidiabetic agents are used with Kapril may cause a decrease in the blood sugar level. The blood glucose levels should be monitored carefully in such patients.

Kapril Tablet interacts with drugs which increase vascular smooth muscle tone and stimulates the sympathetic nervous system (vasopressor sympathomimetics). The use of vasopressor sympathomimetics (for example, isoproterenol, dobutamine, dopamine, adrenaline) with Kapril may reduce the blood lowering effect of Kapril. The blood pressure should be monitored in such patients.

Special instructions need to be followed while taking this medicine along with drugs that may change the blood cell count. The use of drugs that may change the blood cell count (such as allopurinol, corticosteroids, immunosuppressants, cytostatics, procainamide) with Kapril may cause an increase in the chances of occurrence of blood reactions.

There may be an interaction of Kapril with potassium salts, potassium-sparing diuretics, heparin and other, which increases the potassium level. When using Kapril with potassium salts, potassium-sparing diuretics (spironolactone, triamterene, amiloride and others), heparin and other potassium level increasing substances (angiotensin II antagonists, ciclosporin, trimethoprim, tacrolimus), an increase in the level of potassium salt may occur. Take caution while using Kapril together with potassium salts, potassium-sparing diuretics, heparin and other, which increases the potassium level. The potassium level should be closely monitored in such patients.

Kapril Tablet may interact with the mammalian target of rapamycin (mTOR) inhibitors, which are used to suppress the immune system. The patient’s taking mTOR inhibitor (for example, temsirolimus) with Kapril are at increased risk of swelling of the lower skin due to fluid accumulation.

Kapril Tablet may interact with telmisartan, which is used to treat high blood pressure. The combined use of Kapril with telmisartan leads to abnormal functioning of the kidney, which can be possibly fatal. The combined use of Kapril with telmisartan is not recommended in such patients.

There may be an interaction of Kapril with thiazide diuretics, which are used to treat high blood pressure and swelling due to fluid accumulation. Kapril can reduce the potassium loss caused by thiazide diuretics. Proper monitoring of potassium levels in the blood is required in such patients.

This page does not contain all the possible interactions of Kapril Tablet. Share a list of all medicines that you use with your doctor and pharmacist. Do not start, stop, or change the dose of any medicines without the approval of your doctor.

Serious

The following medicines may interact when taken together and can cause harmful effects in the body. Please consult with your doctor or pharmacist before taking these medicines together.

• mTOR Inhibitor Immunosuppressant
• Gold

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