Fluvermal инструкция на русском отзывы - Инструкции, руководства, мануалы

Fluvermal: Flubendazole – Anthelmintic

Composition

Each tablet or 5 ml suspension contains: 100 mg Flubendazole.

Properties

Fluvermal is a synthetic broad spectrum anthelmintic. Fluvermal interferes with cellular tubulin formation in the worm, thus disturbing glucose uptake and the normal digestive functions of the worm to such an extent that an autolytic process occurs.

Flubendazole is poorly absorbed after oral administration. At the normal anthelmintic dosage, the bioavailability is poor because of the combination of high first-pass metabolism and a very low solubility of the drug. 90% of the small fractions that is absorbed is bound to plasma proteins.

Indications & Usage

Fluvermal is indicated for the treatment of single or mixed infestations by:

Enterobius vermicularis (threadworm/ pinworm)
Trichuris trichiura (whipworm)
Ascaris lumbricoides (large round worm)
Ancylostoma duodenale and Necator americanus (hookworm).

Contraindications

Fluvermal is contraindicated in persons who have shown hypersensitivity to the drug.

Side Effects

Only minor Side Effects to Fluvermal have been reported.

Transient abdominal pain and diarrhoea have rarely only been reported, in cases of massive infestations and expulsion of worms.

Hypersensitivity reactions such as exanthema, rash, urticaria and angio-oedema have rarely been observed.

Warnings & precautions

Use in infants < 1 year: As well-documented experience in children below 1 year of age is scarce, Fluvermal should only be given to very young children if their worm infection interferes significantly with their nutritional status and physical development.

Use during pregnancy and lactation: Although Flubendazole gives no evidence of teratogenic properties in animals, possible risks from Flubendazole during pregnancy should be weighed against the expected therapeutic benefits, particularly during the first trimester.

It is not known whether Flubendazole is excreted in human milk. Therefore caution should be exercised when Fluvermal is administered to nursing women.

Overdose

In the event of accidental overdosage, abdominal cramps, nausea, vomiting and diarrhoea may occur.

Although the maximum recommended treatment duration of Fluvermal is limited to 3 days there have been rare reports of reversible liver function disturbances, hepatitis and blood dyscrasias described in patients who were treated for hydatid disease with massive doses for prolonged periods of time.

There is no specific antidote. Gastric lavage with aqueous potassium permanganate at 20 mg/ 100 ml may be performed. Activated charcoal may be given.

Dosage & Administration

1- Enterobiasis: 1 tablet or 5 ml drinkable suspension given as a single dose. since reinfections by Enterobius vermicularis are very common, it is recommended that the treatment be repeated after 2 and 4 weeks, particularly in eradication programmes.

2-Ascariasis, Trichuriasis, Anchylostomiasis and mixed infections: 1 tablet b.i.d or 5 ml drinkable suspension morning and evening for 3 consecutive days. The dosages above apply to children as well as adults. No special procedures, such as diet or use of laxatives are required.

For infants< 1 year, see under Warnings and Precautions.

Packing

Tablets Pack contains 1 or 167 strips X 6 tablets.
Suspension: Pack contains bottle of 30 ml

Storage

For Tablets: Store in a dry place, away from light at a temperature between 15-30 °C.
For Suspension: Store in airtight container, away from light at a temperature between 15-30 °C.

Medicament is a product which affects your health, and its consumption contrary to instructions is dangerous for you.
Follow strictly the doctor’s prescription, the method of use and the instructions of the pharmacist who sells the medicament.
The doctor and the pharmacist are experts in medicine, its benefits and risks.
Do not by yourself interrupt the period of treatment prescribed for you.
Keep medicament out of reach of children
Do not repeat the same prescription without consulting your doctor.

Council of Arab Health Ministers and Union of Arab Pharmacists

Produced by:Janssen Pharmaceuticals (Janssen-Cilag) -Egypt. ATC Code: P02CA05

Источник

1 саше содержит:

2,5 х 109 КОЕ Lactobacillus plantarum LP01; 2,5 х 109 КОЕ Lactobacillus plantarum LP02; 2,5 х 109 КОЕ Lactobacillus rhamnosus LR04; 2,5 х 109 КОЕ Lactobacillus rhamnosus LR05;

5 х 109 КОЕ Bifidobacterium lactis BS01 (всего 15 х 109 КОЕ жизнеспособных бактерий).

вспомогательные вещества: фруктоолигосахариды – 3000 мг, нерастворимая клетчатка – 225,9 мг, картофельный мальтодекстрин (загуститель) – 322 мг, кремния диоксид (эмульгатор) – 7,1 мг.

Флувир / Fluvir® представляет собой комбинацию пробиотиков — Lactobacillus plantarum LP01и LP02, Lactobacillus rhamnosus LR04 и LR05, Bifidobacterium lactis BS01 и пребиотика — фруктоолигосахаридов.

Сочетание пробиотиков и пребиотика позволяет действовать гораздо эффективнее простых пробиотиков. Наличие питательной среды (фруктоолигосахаридов) продлевает жизнь пробиотических бактерий и увеличивает количество собственных полезных бактерий организма человека, что помогает нормализовать микрофлору кишечника, улучшить его функциональное состояние при запорах, вздутии живота, обеспечить нормальное пищеварение.

Входящие в состав Флувир / Fluvir® пробиотические бактерии способствуют повышению общей сопротивляемости организма к наиболее распространённым в зимний период вирусным и бактериальным инфекциям верхних дыхательных путей, предупреждают дисбиоз и антибиотик-ассоциированную диарею во время и после приема антибиотиков, развитие пищевой аллергии.

Lactobacillus plantarum LP01 и LP02, Lactobacillus rhamnosus LR04 и LR05 и Bifidobacterium lactis BS01:

проявляют иммуномодулирующие свойства: усиливают специфический IgA-ответ и снижают выработку цитокинов, связанных с воспалением; синтезируют аминокислоты, пантотеновую кислоту, витамины К и группы В; способствуют всасыванию железа, кальция, витамина D;
проявляют симбиоз, компенсируя метаболизм друг друга, и стимулируют взаимный рост; обладают высокой антагонистической активностью против широкого спектра патогенных и условно-патогенных микроорганизмов, угнетают жизнедеятельность стафилококков, шигелл, ротавирусов, протея, энтеропатогенной кишечной палочки, некоторых дрожжеподобных грибов, препятствуют их адгезии к слизистой оболочке кишечника;
создают благоприятные условия для развития полезной микрофлоры кишечника, поддерживают и регулируют физиологическое равновесие кишечной микрофлоры, способствуют нормализации микробиоценоза желудочно-кишечного тракта.

Lactobacillus plantarum LP01 и LP02, Lactobacillus rhamnosus LR04 и LR05 способствуют расщеплению углеводов в просвете кишечника с образованием молочной кислоты. Созданная таким образом кислая среда благотворно влияет на развитие собственных бифидобактерий организма — составляющих 85-95% микрофлоры кишечника организма как у взрослого, так и у ребенка.

Рекомендуется в качестве биологически активной добавки к рациону питания детей с 1-го месяца жизни и взрослых как дополнительный источник жизнеспособных молочнокислых бактерий Lactobacillus и Bifidobacterium.

Перед применением рекомендуется проконсультироваться с врачом.

Содержимое одного саше растворить в 100 мл теплой питьевой воды. По рекомендации врача принимать детям с 1-го месяца жизни и взрослым по 1-2 саше в сутки во время еды.

Содержимое саше можно добавлять в грудное молоко или молочную детскую смесь.

Не добавлять к горячему! Не изменяет вкус напитков и еды. Курс применения – 1 месяц или по рекомендации врача.

Индивидуальная непереносимость компонентов продукта.

Через аптечную сеть, специализированные магазины и отделы торговой сети.

Порошок по 3,93 г в саше в картонной коробке №2, №10, №20.

Хранить в сухом, защищенном от света и недоступном для детей месте при температуре от 15ºС до 25ºС.

Не требует хранения в холодильнике!

24 месяца от даты производства.

Не является лекарством.

№KZ.16.01.78.003.Е.003648.12.13 от 24.12.2013г.

Probiotical S.p.A, Виа Матеи 3, Новара, 28100, Италия для Delta Medical Promotions AG, Отенбахгассе 26, Цюрих 8001, Швейцария.

FLUVIR, SCHONEN, proBioSWISS – зарегистрированные товарные знаки Delta Medical Promotions AG, Switzerland / Дельта Медикел Промоушнз АГ, Швейцария.

BIOTHERAPEUTIC PROBIOTICAL – торговая марка компании Probiotical S.p.A, Италия.

Источник

Fluvermal
ANTHELMINTIC

Description :

Fluvermal is a synthetic broad- spectrum anthelmintic.
Fluvermal is available as oral tablets containing 100 mg flubendazole and as a drinkable suspension containing
20 mg flubendazole per ml. Chemically, flubendazole is methyl 5-(p-fluorobenzoyl)- 2-benzimidazolecarbamate with a molecular weight of
313.29.

Properties:

Fluvermal interferes with cellular tubulin formation in the worm, thus disturbing glucose uptake and the normal digestive functions of the worm to such an extent that an autolytic process occurs. Flubendazole is poorly absorbed after oral administra- tion. At the normal anthel-nintic dosage, the bioavailability is poor because of the combination of high first-pass metabolism and a very low solubility of the drug. 90% of the small fraction that is absorbed is bound to plasma proteins.

Indications:

Fluvermal is indicated for the treatment of single or mixed infestations by Enterobius vermicularis (thread- worm/pinworm); Trichuris trichiura (whipworm); Ascaris lumbricoides (large roundworm); Ancylostoma duodena le, Necator americanus (hookworm).

Contra-Indications:

Fluvermal is contraindicated in persons who have shown hypersensitivity to the drug.

Adverse reactions:

Only minor adverse reactions to FLUVERMAL have been reported. Transient abdominal pain and diarrhoea have only rarely been reported, in cases of massive infestation and ex- pulsion of worms. Hypersensitivity reactions such as exanthema, rash, urticaria and angio-oedema have rarely been observed.

Precautions:

Use in infants <1 year: As well-documented experience in children below 1 year of age is scarce, Fluvermal should only be given to very young children if their worm infection interferes Significantly with their nutritional stat- us and physical development.

Use during pregnancy and lactation:

Although Fluvermal gives no evidence of teratogenic properties in animals, possible risks from Fluvermal during pregnancy should be weighed against the expected therapeutic benefits, particularly during the first trimester. It is not known whether Fluvermal is excreted in human milk. Therefore caution should be exercised when Fluvermal is administered to nursing women.

Dosage and Administration:

1) Enterobiasis: 1 tablet or 5 ml drinkable suspension given as a single dose.
Since reinfections by Enterobius vermicularis are very common, it is recommended that the treatment be re- peated after 2 and 4 weeks, particularly in eradication programmes.
2) Ascariasis, trichuriasis, ancylostomiasis and mixed in- fections: 1 tablet b.i.d. or 5 ml drinkable suspension morning and evening for 3 consecutive days. The dosages above apply to children as well as adults. No special procedures, such as diet or use of laxatives, are required. For infants <1 year, see underPrecautions.

Overdosage:

In the event of accidental overdosage, abdominal cramps, nau e ,vomittng-and diarrhoea mavet:HAlthough the maximum recommended treatment dura-
tion of Fluvermal is limited to three days there have been ” rare reports of reversible “liver function “disturbances, hepatitis and blood dyscrasias described in patients who were treated for hydatid disease with massive doses for prolonged periods of time. There is no specific antidote. Gastric lavage with aque- ous potassium permanganate at 20 mg/100 ml may be performed. Activated charcoal may be given.

How supplied:

Fluvermal tablets (each containing 100 mg flubendazole) is supplied in packs of 18 tablets. Fruvermal drinKable suspension (contalnrng 0 mg-per ml) is supplied in bottles of 30 ml. The suspension should be shaken before use.
Store between 15_0 and 300 C. Protect from light.

produced by :

JANSSEN-ClLAG
MINAPHARM
Under licence of
JANSSEN PHARMACEUTICA· Belgium

فلوفيرمال عقار مضاد للديدان مثل الدودة الدبوسية والسوطية والمدورة

Источник

Primary Application

Imprint

For what

Cleanse/Restore the Body

Source

Allopathy

For whom

People

This compound belongs to the group of benzimidazole carbamates, drugs widely used in human and veterinary medicine against parasitic worms. The molecular mechanism of action of flubendazole is based on its specific binding to tubulin, which results in disruption of microtubule structure and function, and in the interference with the microtubule-mediated transport of secretory vesicles in absorptive tissues of helminths. The microtubule-disrupting properties of

benzimidazole derivatives raised recently interest in these compounds as possible anti-cancer agents. In this minireview, flubendazole

effects towards selected human malignant cells including myeloma, leukemia, neuroblastoma, breast cancer, colorectal cancer, and

melanoma are discussed along with basic data on its pharmacokinetics, metabolism, and toxicity.

Combine this IC with other substances that are known to show anti-cancer effects or substances against parasites. You can support the digestive system with PEMFs and also probiotics.

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FLUVERMAL 100 MG ( FLUBENDAZOLE ) 18 TABLETS

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You can return the product within 14 days of purchase.

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You can return the product within 14 days of purchase.

FLUVERMAL 100 MG ( FLUBENDAZOLE ) 18 TABLETS

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Fluvermal tablets description :

It is a synthetic broad- spectrum anthelmintic.
It is available as oral tablets containing 100 mg flubendazole and as a drinkable suspension containing 20 mg flubendazole per ml. Chemically, flubendazole is methyl 5-(p-fluorobenzoyl)- 2-benzimidazolecarbamate with a molecular weight of 313.29.

Fluvermal tablets

Fluvermal tablets properties:

It interferes with cellular tubulin formation in the worm, thus disturbing glucose uptake and the normal digestive functions of the worm to such an extent that an autolytic process occurs. Flubendazole is poorly absorbed after oral administration. At the normal dosage, the bioavailability is poor because of the combination of high first-pass metabolism and a very low solubility of the drug. 90% of the small fraction that is absorbed is bound to plasma proteins.

Fluvermal tablets indications:

It is indicated for the treatment of single or mixed infestations by Enterobius vermicularis (thread- worm/pinworm); Trichuris trichiura (whipworm); Ascaris lumbricoides (large roundworm); Ancylostoma duodenale, Necator americanus (hookworm).

Fluvermal tablets contra-Indications:

It is contraindicated in persons who have shown hypersensitivity to the drug.

Fluvermal tablets adverse reactions:

Only minor adverse reactions to it have been reported. Transient abdominal pain and diarrhoea have only rarely been reported, in cases of massive infestation and expulsion of worms. Hypersensitivity reactions such as exanthema, rash, urticaria and angio-oedema have rarely been observed.

Fluvermal tablets precautions:

Use in infants <1 year: As well-documented experience in children below 1 year of age is scarce, it should only be given to very young children if their worm infection interferes significantly with their nutritional status and physical development.

Fluvermal tablets use during pregnancy and lactation:

Although it gives no evidence of teratogenic properties in animals, possible risks from it during pregnancy should be weighed against the expected therapeutic benefits, particularly during the first trimester. It is not known whether it is excreted in human milk. Therefore caution should be exercised when it is administered to nursing women.

Fluvermal tablets dosage and administration:

Fluvermal tablets overdosage:

In the event of accidental overdosage, abdominal cramps, nausea ,vomittng and diarrhoea occurs. Although the maximum recommended treatment duration of it is limited to three days there have been rare reports of reversible liver function disturbances, hepatitis and blood dyscrasias described in patients who were treated for hydatid disease with massive doses for prolonged periods of time. There is no specific antidote. Gastric lavage with aque- ous potassium permanganate at 20 mg/100 ml may be performed. Activated charcoal may be given.

How supplied:

Fluvermal tablets (each containing 100 mg flubendazole) is supplied in packs of 18 tablets. Fruvermal suspension (contalnrng 0 mg-per ml) is supplied in bottles of 30 ml. The suspension should be shaken before use.
Store between 15 and 30 C. Protect from light.

Produced by :

JANSSEN-ClLAG
MINAPHARM
Under licence of
JANSSEN PHARMACEUTICA· Belgium.

Источник

Composition

Properties

Indications & Usage

Contraindications

Side Effects

Warnings & precautions

Overdose

Dosage & Administration

Packing

Storage

فلوفيرمال عقار مضاد للديدان مثل الدودة الدبوسية والسوطية والمدورة

Example

Write a review

Fluvermal tablets description :

Fluvermal tablets properties:

Fluvermal tablets indications:

Fluvermal tablets contra-Indications:

Fluvermal tablets adverse reactions:

Fluvermal tablets precautions:

Fluvermal tablets use during pregnancy and lactation:

Fluvermal tablets dosage and administration:

Fluvermal tablets overdosage:

How supplied:

Produced by :

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