Торговое название:
Альфинтерн
Alphintern
Состав:
Каждая таблетка содержит:
Трипсин и химотрипсин комплекс 12 мг
Вспомогательные компоненты:
Крахмал, аеросил, магний стеарат, авицель, метилцеллюлоза, декстран, тальк.
Свойства:
Протеолитическое комбинированное средство белковой природы. Получают из поджелудочной железы крупного рогатого скота. При местном и наружном применении расщепляет некротизированные ткани и фибринозные образования; разжижает вязкий секрет, экссудат, сгустки крови. Гидролизует белки и пептоны с образованием низкомолекулярных пептидов, расщепляет связи, образованные остатками ароматических аминокислот (тирозин, троптофан, фенилаланин, метионин).
Показания:
Уменьшение и ресорбция отеков и экссудатов.
Адъюнктотерапия при воспалительных заболеваниях.
Способ применения и дозы:
По 1 или 2 таблетки 3 раза в сутки.
Противопоказания:
Гиперчувствительность, злокачественные новообразования, деструктивные формы туберкулеза легких, ХСН II–III ст., эмфизема легких с дыхательной недостаточностью.
Меры предосторожности :
Эмпиема плевры туберкулезной этиологии (рассасывание экссудата может способствовать развитию бронхоплевральной фистулы).
Побочные эффекты:
Аллергические реакции.
Повышение температуры тела, тахикардия.
Может появиться раздражение слизистых оболочек верхних дыхательных путей и охриплость голоса.
Способ хранения:
В сухом прохладном месте при температуре не выше 30 градусов.
Упаковка:
Картонная коробка вмещает 1,2,3 блистера по 10 таблеток.
Каждая таблетка содержит активное вещество — Бетагистин дигидрохлорид 8 мг или 16 мг и вспомогательные вещества — лактозу моногидрат, крахмал кукурузный, целлюлозу микрокристаллическую, кислоту лимонную безводную, повидон, кросповидон, гидрогенизированное растительное масло.
Таблетки 8 мг: белые гладкие круглые таблетки с фаской и разделительной риской; диаметр 6,5 мм. Таблетки 1 б мг: белые гладкие круглые таблетки с фаской и разделительной риской; диаметр 9,0 мм.
Бетагнстин дигидрохлорид синтетический аналог гистамина, обеспечивает улучшение микроциркуляпии в лабиринте, с последующим снижением эндолимфатического давления. Действует главным образом на гистаминовые Н,- и Н, — рецепторы внутреннего уха и вестибулярных ядер ЦНС. Путем прямого агонистического воздействия на Н, — рецепторы сосудов внутреннего уха, а также опосредовано через воздействие на Н3 — рецепторы улучшает микроциркуляцию и проницаемость капилляров, тем самым нормализует давление эндолимфы в лабиринте и улитке. Вместе с тем увеличивает кровоток в базилярных артериях.
Бетагистин дигидрохлорид также обладает выраженным центральным эффектом, являясь ингибитором Н. — рецепторов ядер вестибулярного нерва. Нормализует нейрональную трансмиссию в лолисинаптических нейронах вестибулярных ядер на уровне ствола головного мозга.
После перорального приема Алфинора он быстро и полностью абсорбируется. С,^ в плазме достигается через 3 часа. Связывание с белками плазмы низкое, Т|Я — 3-4часа. Выводится с мочой в виде метаболита 2-пиридилксусной кислоты в течение 24 часов после приема. Неизмененный бетагистидин дигидрохлорид в моче не определяется.
Болезнь и синдром Меньера (в т. ч. шум в ушах и нарушения слуха), вестибулярные головокружения различного генеза (вертебробазилярная недостаточность, посттравматическая энцефалопатия, атеросклероз сосудов головного мозга, вестибулярный неврит, лабиринтит, доброкачественное позиционное головокружение, после нейрохирургических операций), нейросенсорная тугоухость различного генеза, морская и воздушная болезнь.
Язвенная болезнь желудка в фазе обострения, феохромоцитома, бронхиальная астма, повышенная чувствительность к компонентам препарата, детский возраст. Не рекомендуется принимать препарат в период беременности и лактации.
Таблетки принимают перорально, запивают водой, предпочтителен прием препарата с едой.
Взрослые:
Начальная доза составляет 8-16 мг 3 раза в день. Доза может корректироваться в соответствии с клиническим результатом. Поддерживающая доза обычно составляет 24-48 мг в день, разделенная на 3 равных приема.
Улучшение обычно отмечается уже в начале терапии, стабильный терапевтический эффект наступает после двух недель лечения и может нарастать в течение нескольких месяцев лечения. Лечение длительное.
Длительность приема препарата подбирается индивидуально.
Поэклтые пациенты:
Применяют обычную дозу для взрослых. Печеночная недостаточность: Корректировка дозы не требуется. Почечная недостаточность Корректировка дозы не требуется.
Со стороны желудочно-кишечного тракта: диспепсия, боль в животе/спазмы, тошнота, рвота.
Со стороны центральной нервной системы: головная боль; редко — слабость, сонливость, бессонница. Аллергические реакции: редко — кожная сыпь, зуд, крапивница, отек Квинке.
Симптомы:
Диспепсия, боль в животе/спазмы, тошнота, рвота.
Лечение:
Нет специфического антидота для бетагастина дигидрохлорида. Пациент должен находится под наблюдением, лечение симптоматическое и поддерживающее.
Случаи взаимодействия или несовместимости с другими лекарственными средствами неизвестны.
Требуется осторожность при лечении пациентов с язвенной болезнью в анамнезе.
Влияние на способность к вождению автотранспорта и управлению механизмами: Алфинор не влияет на способность пациента к занятиям потенциально опасными видами деятельности, требующими повышенного внимания и быстроты психомоторных реакций.
Таблетки 8 мг №20,30,60,90.
Таблетки 16мг№20,30,60,90.
Хранить в сухом месте при температуре не выше 25“С.
Беречь от детей.
3 года. Не использовать позже срока годности, указанного на упаковке.
Отпускается по рецепту врача.
Alphintern may be available in the countries listed below.
Ingredient matches for Alphintern
Chymotrypsin
Chymotrypsin is reported as an ingredient of Alphintern in the following countries:
- Egypt
- Kuwait
Trypsin
Trypsin is reported as an ingredient of Alphintern in the following countries:
- Egypt
- Kuwait
Important Notice: The Drugs.com international database is in BETA release. This means it is still under development and may contain inaccuracies. It is not intended as a substitute for the expertise and judgement of your physician, pharmacist or other healthcare professional. It should not be construed to indicate that the use of any medication in any country is safe, appropriate or effective for you. Consult with your healthcare professional before taking any medication.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Medical Disclaimer
- Overview
- Uses
- Side-effects
- Precautions
- Interactions
- Contraindications
Overview
Alphintern Tablet works by reducing swelling and destruction of tissues; absorbing proteins into blood thus helping in digestion and removing dead tissues thus healing wounds;
Detailed information related to Alphintern Tablet’s uses, composition, dosage, side effects and reviews is listed below.
Uses
Side-effects
The following is a list of possible side-effects that may occur from all constituting ingredients of Alphintern Tablet. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.
- Swelling in the mouth
- Breathing difficulty
- Rash
- Hypersensitivity reactions
- Chill
- Inflammation of the uvea
- Swelling of the cornea
- Tightness in the chest
- Swelling of the mouth
- Hives
- Difficulty breathing
- Tongue
- Itching
- Temporary stinging sensation
- Pain
- Burning sensation
- Alphintern Tablet may also cause side-effects not listed here.
If you notice other side-effects not listed above, contact your doctor for medical advice. You may also report side-effects to your local food and drug administration authority.
Precautions
Before using Alphintern Tablet, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.
- Avoid contact with eyes
- Consult your doctor if you have severe liver or kidney disease
- Take caution if you are allergic to it
Interactions with Alphintern Tablet
Please consult your physician or pharmacist or product package for this information.
When not to use Alphintern Tablet
Hypersensitivity to Alphintern Tablet is a contraindication. In addition, Alphintern Tablet should not be used if you have the following conditions:
- Breastfeeding
- Fresh blood clots
- High vitreous pressure
- Hypersensitivity
- Kidney impairment
- Peptic ulcer
- Pregnant
- Severe liver
Composition and Active Ingredients
Alphintern Tablet is composed of the following active ingredients (salts)
- Chymotrypsin
- Trypsin
Please note that this medicine may be available in various strengths for each active ingredient listed above.
Packages and Strengths
Alphintern Tablet is available in the following packages and strengths
Alphintern Tablet — Packages: 20s (10s Blister x 2)
Frequently asked Questions
-
Is Alphintern Tablet safe to use when pregnant?
- Chymotrypsin: Please consult with your doctor for case-specific recommendations.
- Trypsin: No
-
Is Alphintern Tablet safe while breastfeeding?
- Chymotrypsin: Please discuss the risks and benefits with your doctor.
- Trypsin: No
-
Can Alphintern Tablet be used for osteoarthritis and digestive problems?
Yes, osteoarthritis and digestive problems are among the most common reported uses for Alphintern Tablet. Please do not use Alphintern Tablet for osteoarthritis and digestive problems without consulting first with your doctor. Click here and view survey results to find out what other patients report as common uses for Alphintern Tablet.
-
How long do I need to use Alphintern Tablet before I see improvement of my conditions?
TabletWise.com website users have reported same day and 1 week as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Alphintern Tablet. Click here and view survey results to find out what other patients report as time for effectiveness for Alphintern Tablet.
-
At what frequency do I need to use Alphintern Tablet?
TabletWise.com website users have reported thrice a day and twice a day as the most common frequency of using Alphintern Tablet. Please follow your doctor’s advice on how often you need to Alphintern Tablet. Click here and view survey results to find out what other patients report as frequency of using Alphintern Tablet.
-
Should I use Alphintern Tablet empty stomach, before food or after food?
TabletWise.com website users have most commonly reported using Alphintern Tablet before food. However, this may not be reflective of how you should use this medicine. Please follow your doctor’s advice on how you should use this medicine. Click here and view survey results to find out what other patients report as timing of using Alphintern Tablet.
-
Is it safe to drive or operate heavy machinery when using this product?
If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Alphintern Tablet medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Alphintern Tablet. Always consult with your doctor for recommendations specific to your body and health conditions.
-
Is this medicine or product addictive or habit forming?
Most medicines don’t come with a potential for addiction or abuse. Usually, the government’s categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body’s dependence to medicines without the advice of a doctor.
-
Can i stop using this product immediately or do I have to slowly wean off the use?
Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.
Other important Information on Alphintern Tablet
Missing a dose
In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.
Overdosage of Alphintern Tablet
- Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Alphintern Tablet, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.
- Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.
- Please consult your physician or pharmacist or product package for more information.
Storage of Alphintern Tablet
- Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.
- Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Alphintern Tablet.
Expired Alphintern Tablet
- Taking a single dose of expired Alphintern Tablet is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drugs. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.
Dosage Information
Please consult your physician or pharmacist or refer to the product package.
Cite this page
Page URL
HTML Link
APA Style Citation
- Alphintern Tablet — Product — tabletwise.net. (n.d.). Retrieved April 20, 2023, from https://www.tabletwise.net/uae/alphintern-tablet
MLA Style Citation
- «Alphintern Tablet — Product — tabletwise.net» Tabletwise.com. N.p., n.d. Web. 20 Apr. 2023.
Chicago Style Citation
- «Alphintern Tablet — Product — tabletwise.net» Tabletwise. Accessed April 20, 2023. https://www.tabletwise.net/uae/alphintern-tablet.
Last updated date
This page was last updated on 9/27/2020.
This page provides information for Alphintern Tablet Product in English.
-
Osteoarthritis
Osteoarthritis is the most common form of arthritis. It causes …
-
Fractures
A fracture is a break, usually in a bone. If the broken bone …
-
Peptic Ulcer
A peptic ulcer is a sore in the lining of your stomach or your …
-
Cataract
A cataract is a clouding of the lens in your eye. It affects …
Alphintern® gastroresistant and enterosoluble coated tablet
Composition
Each tablet contains:
- CyclospChymotrypsin 300 E.A.U. (14µ Katals).
- Trypsin 300 E.A.U. (5µ Katals).
Excipient q.s. ad one coated tablet of 0.24g gastroresistant and enterosoluble.
Properties
Alphintern® has a synergistic, anti-inflammatory and antiedematous action of two potent proteolytic enzymes, affecting the exudative phase of inflammation and ensuring the destruction of peptidic chains in inflammatory processes, regardless of the origin.
The gastroresistant and enterosoluble coating of alphintern® tablets ensures best tolerability as well as best efficacy due to its absorption only in the intestine.
Indications
Preventive and curative treatment of post-traumatic and postoperative edemas and hematomas.
Inflammatory conditions and related pains regardless of the origin and localization, especially in:
- Traumatology and Surgery: Sprains, hematomas, sequelae of fractures and postoperative edemas.
- E.N.T.: Pharyngitis, laryngitis, sinusitis, otitis and inflammations of the Eustachian tube.
- Ophthalmoloty: Eye trauma, postoperative and vitreous hemorrhage
- Pneumology: Bronchopulmonary inflammations and tracheobronchitis
- Stomatology: Teeth extractions, periodontium and gum inflammations, and stomatological and maxillofacial surgery
- Gynecology: Pelvic inflammatory diseases, perineal edema and mastitis.
alphintern® also improves the diffusion in situ of antibiotics, especially in the E.N.T. bronchopulmonary and stomatological spheres.
Contraindications
Known hypersensitivity to trypsin and chymotrypsin.
Precautions
In case of infections, alphintern® should be associated with antibiotics.
Dosage and Administration
One to two tablet 3 minutes daily to be swallowed and not chewed, or as prescribed by the physician.
How Supplied
Strip of 10 tablets in packs of 2 strips.
Keep all medicaments out of reach of children
Product of: AMOUN PHARMACEUTICAL CO. El-Obour City, Cairo, Egypt. ATC Code: S01KX01, B06AA04, M09AB52
Find A Medicine, Tablet
Rated 4.67 out of 5 based on 3 customer ratings
(3 customer reviews)
54.00 EGP
each tablet contains : Chymotrypsin : 300 E.A.U. (14 micro katals ) – Trypsin : 300 E.A.U. (5 micro katals ) . – exipient q.s. ad one coated tablet of 0.24 g,gastroresistant and enterosoluble .
-
Description
-
Additional information
-
Reviews (3)
ALPHINTERN 30 TAB
chymotrypsin, trypsin, anti inflammatory agents .
ALPHINTERN 30 TAB
ACTIVE-INGREDIENT
each tablet contains : Chymotrypsin : 300 E.A.U. (14 micro katals ) – Trypsin : 300 E.A.U. (5 micro katals ) . – exipient q.s. ad one coated tablet of 0.24 g , gastroresistant and enterosoluble .
INDICATION of ALPHINTERN
– Inflammatory conditions and related pain regardless of the origin and localization, especially in: Traumatology & Surgery: Preventive and curative treatment of post- traumatic and postoperative edemas and hematomas Sprains, hematomas, sequelae of fractures and postoperative edemas E.N.T.:
Pharyngitis, laryngitis, sinusitis, otitis and inflammations of the eustachean tube
Ophthalmology: Eye trauma, postoperative and vitreous hemorrhage.
Pneumology: Bronchopulmonary inflammations and tracheobronchitis.
Stomatology: Teeth extractions, periodontium and gum inflammations, and stomatological and maxillofacial surgery.
Gynecology: Pelvic inflammatory diseases, perineal edema and mastitis
DOSAGE
Follow all directions given to you by your pharmacist or doctor carefully . They may differ from the information contained in this leaflet
Ask your pharmacist or doctor for help if you do not understand the instructions on the box .
Recommended dose of ALPHINTERN 30 TAB
one to two tablets 3 times daily to be swallowes and not chewed , or as prescribed by the physician .
CONTRA-INDICATION
known hypersensitivity to trypsin or chymotrypsin .
STORAGE
keep all medications out of reach of children.
PACK
strips of 10 tablets in packs of 2 or 3 strips .
MANUFACTURED BY
AMOUN PHARMACEUTICAL CO . S.A.E .
LEAFLET FOR ALPHINETRN | نشرة Tablet الفينترن
http://www.nerhadou.com/FERROTRON_CHILDREN.html
Read More
https://gardeniapharmacies.com/category/medicine-2/
| Form |
Tablet |
|---|---|
| How to use |
Oral use |